A 55-year-old gentleman was referred to our hospital in a state of shock. He was admitted to a nursing home, a day prior, with history of sudden onset of profuse vomiting, bloody diarrhea and altered sensorium and developed hypotension and oliguria, after a couple of hours. He was treated with intravenous fluids, antibiotics and vasopressors. He did not show much improvement over the day & hence was referred to our hospital. On evaluation of the symptoms, in detail, he was asymptomatic until 7 am, at which time he consumed a glass of bottle gourd juice as was his daily routine. He noticed the juice to be unusually bitter, and developed symptoms after 30 minutes. He had past history of Diabetes and Ischemic heart disease. He was on oral hypoglycemic drugs, antiplatelets and statins.Toxicity with bottle gourd, which is bitter tasting, can occur in some as it is a commonly consumed vegetable and it may be actually more common than reported in literature. It presents with abdominal discomfort, hematemesis, hypotension with or without organ dysfunction which starts within approximately 30 min after consumption of the bottle gourd or its juice. It may be easily confused with other illnesses like GI sepsis which have similar presentation. Increasing public awareness about the dangerous effects of consumption of bitter bottle gourd will prevent further cases.